Description
Fingolimod (FTY 720) is an immunomodulatory agent can be phosphorylated by SphK, then functions as a potent agonist of S1P receptors (S1P1/3/4/5) with EC50 of 0.3-5nM; has no affitnity for S1P2; alters lymphocyte trafficking and inhibits lymphocyte recirculation. Multiple Sclerosis Approved